Φαρμακευτικός Κόσμος, Συμπληρώματα Διατροφής

29 Vitamin or mineral Drug Type of interaction Magnesium amikacin, dibekacin, gentamicin, kanamycin, netilmicin, streptomycin, tobramycin Neuromuscular weakness cisatracurium, rapacuronium, succinylcholine, vecuronium Enhanced neuromuscular blockade dicumarol Increased risk of bleeding didanosine, mefenamic acid, quinidine, rocuronium Increased risk of adverse drug effects felodipine, isradipine Hypotension glipizide, glyburide, nicardipine, nifedipine Hypoglycemia labetalol Bradycardia and decreased cardiac output polystyrene sulfonate Increased risk of metabolic alkalosis levomethadyl Increased risk of QT prolongation tacrolimus Increased drug exposure Iron acetohydroxamic acid, cefdinir, cinoxacin, ciprofloxacin, demeclocycline, doxycycline, gatifloxacin, gemifloxacin, grepafloxacin, ibandronate, levodopa, levofloxacin, lomefloxacin, methacycline, methydopa, minocycline, moxifloxacin, mycophenolate mofetil, norfloxacin, ofloxacin, oxytetracycline, penicillamine, rolitetracycline, temafloxacin, tetracycline, trovafloxacin mesylate Decreased drug effectiveness acetohydroxamic acid, aluminum carbonate basic, aluminum hydroxide, aluminum phosphate, calcium, chloramphenicol, cholestyramine, demeclocycline, dihydroxyaluminum aminoacetate, dihydroxyaluminum, sodium carbonate, doxycycline, enoxacin, magaldrate, magnesium oxide, magnesium trisilicate, methacycline, minocycline, oxytetracycline, rolitetracycline, sodium bicarbonate, tetracycline Decreased iron effectiveness etidronate, sparfloxacin, trientine, zinc Reduced drug absorption gossypol, soy protein, trientine, zinc Reduced iron absorption esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole Reduced iron bioavailability levothyroxine Hypothyroidism Zinc cinofloxacin, ciprofloxacin, enoxacin, gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, tetracycline Decreased drug effectiveness gemifloxacin, sparfloxacin Decreased drug absorption penicillamine Decreased zinc absorption copper Decreased zinc or cooper absorption iron Decreased zinc or iron absorption MICROMEDEX HealthCare Series, 2006: Vol 128. Greenwood Village, CO: Τhomson MICROMEDEX